Product Name :
3,5-Di-O-caffeoylquinic acid (CAS 2450-53-5)
Synonym :
Isochlorogenic acid
Application :
3,5-Di-O-caffeoylquinic acid is an antioxidant that has been shown to have antiproliferative activity
CAS:
2450-53-5
Purity:
≥97%
Molecular Weight:
516.5
Formula :
C25H24O12
Physical state:
Solid
solubility :
Soluble in DMSO, and 100% ethanol.
Shipping Condition :
Store at -20° C
Melting point:
170-172° C
SMILES:
C1C(C[C@H](C([C@@H]1OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)OC(=O)/C=C/C3=CC(=C(C=C3)O)O)(O)C(=O)O
References:
:Angiotensin converting enzyme inhibitors from Cuscuta japonica Choisy. | Oh, H., et al. 2002. J Ethnopharmacol. 83: 105-8. PMID: 12413714In vitro antioxidative effects and tyrosinase inhibitory activities of seven hydroxycinnamoyl derivatives in green coffee beans. | Iwai, K., et al. 2004. J Agric Food Chem. 52: 4893-8. PMID: 15264931Changes in caffeic acid derivatives in sweet potato (Ipomoea batatas L.) during cooking and processing. | Takenaka, M., et al. 2006. Biosci Biotechnol Biochem. 70: 172-7. PMID: 16428835Neuroprotective effect of 3,5-di-O-caffeoylquinic acid on SH-SY5Y cells and senescence-accelerated-prone mice 8 through the up-regulation of phosphoglycerate kinase-1. | Han, J., et al. 2010. Neuroscience. 169: 1039-45. PMID: 20570715Structure-activity relationship of caffeoylquinic acids on the accelerating activity on ATP production. | Miyamae, Y., et al. 2011. Chem Pharm Bull (Tokyo). 59: 502-7. PMID: 21467684Neuroprotective effects of 3,5-di-o-caffeoylquinic acid in vitro and in vivo. | Han, J. and Isoda, H. 2011. BMC Proc. 5 Suppl 8: P20. PMID: 22373134[Molecular docking of chlorogenic acid, 3,4-di-O-caffeoylquinic acid and 3,5-di-O-caffeoylquinic acid with human serum albumin]. | Zhou, J., et al. 2012. Zhong Xi Yi Jie He Xue Bao. 10: 1149-54. PMID: 23073199Gymnaster koraiensis and its major components, 3,5-di-O-caffeoylquinic acid and gymnasterkoreayne B, reduce oxidative damage induced by tert-butyl hydroperoxide or acetaminophen in HepG2 cells.14871-41-1 web | Jho, EH.21717-96-4 supplier , et al.PMID:33516773 2013. BMB Rep. 46: 513-8. PMID: 24148773NMR Studies of Hetero-Association of Caffeine with di-O-Caffeoylquinic Acid Isomers in Aqueous Solution. | D′Amelio, N., et al. 2015. Food Biophys. 10: 235-243. PMID: 26213521Jasmonates promote enhanced production of bioactive caffeoylquinic acid derivative in Eclipta prostrata (L.) L. hairy roots. | Maciel, G., et al. 2022. Plant Cell Tissue Organ Cult. 149: 363-369. PMID: 34840370Petasites japonicus extract exerts anti-malarial effects by inhibiting platelet activation. | Yun, HS., et al. 2022. Phytomedicine. 102: 154167. PMID: 35598522Biosynthetic studies through feeding experiments in Eclipta prostrata (L.) L. hairy roots. | Lopes, AA., et al. 2022. Plant Cell Tissue Organ Cult. 151: 215-219. PMID: 35875188